Identification of oprG, a gene encoding a major outer membrane protein of Pseudomonas aeruginosa
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منابع مشابه
Identification of oprG, a gene encoding a major outer membrane protein of Pseudomonas aeruginosa.
Sir, Pseudomonas aeruginosa expresses between five and nine major outer membrane proteins (OMPs), depending on the conditions of growth; the genes encoding all but one of these, OprG, have been identified. OprG has an apparent molecular weight of 25,000 when outer membranes are heated to 88°C for 10 min in solubilization buffer before being subjected to SDS–PAGE and 19,000 when they are not pre...
متن کاملThe major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel.
OprG of Pseudomonas aeruginosa is a member of the very large and widely distributed but poorly characterized OmpW (PF0392) family of outer membrane proteins. It was established here that OprG was highly transcribed in anaerobic environments rich in iron via the ANR regulator. In the absence of OprG, P. aeruginosa was significantly less cytotoxic toward human bronchial epithelial cells. Planar b...
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Background & Objectives: Pseudomonas aeruginosa is a common cause of nosocomial infection. OprD protein is a specific protein regulating the uptake of carbapenem antibiotic. Loss of OprD is the main mechanism of Pseudomonas Aeruginosa resistance to carbapenem. In this study, the presence of OprD gene is investigated in isolated Pseudomonas Aeruginosa in burn patients of Ghotboddin hospital in S...
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BACKGROUND The outer membrane (OM) of Gram-negative bacteria provides a barrier to the passage of hydrophobic and hydrophilic compounds into the cell. The OM has embedded proteins that serve important functions in signal transduction and in the transport of molecules into the periplasm. The OmpW family of OM proteins, of which P. aeruginosa OprG is a member, is widespread in Gram-negative bacte...
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background: leptospirosis has been recognized as an important reemerging infectious disease caused by pathogenic leptospira spp. a major challenge of this disease is the application of a basic research to improve diagnostic method. outer membrane proteins of leptospira are potential candidates that could be useful in diagnosis. among them the lipl41 is an immunogenic protein which is present on...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1999
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/43.4.607